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1.
J Hum Nutr Diet ; 33(3): 351-372, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32027072

RESUMO

INTRODUCTION: The aim of this project was to systematically review UK evidence on the effectiveness of long-term (≥12 months) weight management services (WMSs) for weight loss and weight maintenance for adults (≥16 years) with severe obesity (body mass index ≥35 kg m-2 ), who would generally be eligible for Tier 3 services. METHODS: Four data sources were searched from 1999 to October 2018. RESULTS: Our searches identified 20 studies, mostly noncomparative studies: 10 primary care interventions, nine in secondary care specialist weight management clinics and one commercial setting intervention. A programme including a phase of low energy formula diet (810-833 kcal day-1 ) showed the largest mean (SD) weight change at 12 months of -12.4 (11.4) kg for complete cases, with 25.3% dropout. Limitations or differences in evaluation and reporting (particularly for denominators), unclear dropout rates, and differences between participant groups in terms of comorbidities and psychological characteristics, made comparisons between WMSs and inferences challenging. CONCLUSIONS: There is a persistent and clear need for guidance on long-term weight data collection and reporting methods to allow comparisons across studies and services for participants with severe obesity. Data could also include quality of life, clinical outcomes, adverse events, costs and economic outcomes. A randomised trial comparison of National Health Service Tier 3 services with commercial WMSs would be of value.


Assuntos
Bariatria/estatística & dados numéricos , Obesidade Mórbida/terapia , Medicina Estatal/estatística & dados numéricos , Programas de Redução de Peso/estatística & dados numéricos , Adolescente , Adulto , Bariatria/métodos , Terapia Comportamental/métodos , Índice de Massa Corporal , Dieta Redutora/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/fisiopatologia , Resultado do Tratamento , Reino Unido , Programas de Redução de Peso/métodos , Adulto Jovem
2.
Surg Endosc ; 34(7): 3110-3117, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-31435768

RESUMO

INTRODUCTION: Although bariatric center procedural volume has been associated with early perioperative safety, data on the effect of such volume and long-term outcomes after sleeve gastrectomy (SG) are limited. This study aims to examine the relationship between annual bariatric center SG volume and the incidence of revisions or conversions (RC) after SG. METHODS: The New York Statewide Planning and Research Cooperative System database was used to identify all patients who underwent SG between 2006 and 2012. Subsequent RC events were captured up to 2016. Bariatric centers having annual SG volume less than 45, between 45 and 65, and greater than 65 were defined as low (LV), medium (MV), and high volume (HV), respectively. Multivariable Cox proportional hazard regression analysis was performed to compare the risk of having RC among centers with different yearly sleeve volumes. RESULTS: We identified 8389 patients who underwent SG. The overall estimated cumulative incidence of RC was 0.5% (95% CI 0.3-0.6%) at 1 year, 6.2% (95% CI 5.4-7.0%) at 5 years, and 15.3% (95% CI 12.6-18.0%) at 8 years after SG. The estimated cumulative incidence of RC for LV, MV, and HV at 8 years after SG was 16.7% (95% CI 11.1-22.3%), 15.5% (95% CI 11.2-19.8%), and 13.7% (95% CI 9.4-17.9%), respectively. HV centers have lower risk of RC compared to LV (hazard ratio 0.65; 95% CI 0.48-0.88) and MV (hazard ratio 0.75; 95% CI 0.57-0.98). LV and MV centers have comparable risk of RC (hazard ratio 1.15; 95% CI 0.87-1.51). Patients having the initial SG performed in LV were the least likely to have RC in the same institution (46.1% of LV, 13.2% of MV and 22.3% of HV; p < 0.0001). CONCLUSION: Patients undergoing SG at LV centers experience the highest risk of subsequent RC. This effect persists after adjusting for patient-level factors. These data underline the relationship between volume threshold and long-term effect.


Assuntos
Cirurgia Bariátrica/efeitos adversos , Cirurgia Bariátrica/estatística & dados numéricos , Bariatria/estatística & dados numéricos , Gastrectomia/efeitos adversos , Gastrectomia/estatística & dados numéricos , Adulto , Cirurgia Bariátrica/métodos , Conversão para Cirurgia Aberta/estatística & dados numéricos , Feminino , Gastrectomia/métodos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , New York/epidemiologia , Obesidade Mórbida/epidemiologia , Obesidade Mórbida/cirurgia , Modelos de Riscos Proporcionais , Estudos Retrospectivos
3.
Int J Obes (Lond) ; 43(12): 2509-2517, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-30765893

RESUMO

BACKGROUND: Intestinal microbiota have been suggested to play an important role in the pathogenesis of obesity and type 2 diabetes. Bariatric surgery improves both conditions and has been associated with changes in intestinal microbiota composition. We investigated the effect of a nonsurgical bariatric technique on intestinal microbiota composition in relation to metabolic improvement. METHODS: Seventeen patients with obesity and type 2 diabetes were treated with the nonsurgical duodenal-jejunal bypass liner, which excludes the proximal 60 cm small intestine from food. Fecal samples as well as metabolic parameters reflecting obesity and type 2 diabetes were obtained from the patients at baseline, after 6 months with the device in situ, and 6 months after explantation. RESULTS: After 6 months of treatment, both obesity and type 2 diabetes had improved with a decrease in weight from 106.1 [99.4-123.5] to 97.4 [89.4-114.0] kg and a decrease in HbA1c from 8.5% [7.6-9.2] to 7.2% [6.3-8.1] (both p < 0.05). This was paralleled by an increased abundance of typical small intestinal bacteria such as Proteobacteria, Veillonella, and Lactobacillus spp. in feces. After removal of the duodenal-jejunal bypass liner, fecal microbiota composition was similar to that observed at baseline, despite persistent weight loss. CONCLUSION: Improvement of obesity and type 2 diabetes after exclusion of the proximal 60 cm small intestine by treatment with a nonsurgical duodenal-jejunal bypass liner may be promoted by changes in fecal microbiota composition.


Assuntos
Bariatria , Duodeno/fisiologia , Microbioma Gastrointestinal/fisiologia , Jejuno/fisiologia , Obesidade , Adulto , Bariatria/métodos , Bariatria/estatística & dados numéricos , Diabetes Mellitus Tipo 2/fisiopatologia , Diabetes Mellitus Tipo 2/terapia , Fezes/microbiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/fisiopatologia , Obesidade/terapia , Resultado do Tratamento , Adulto Jovem
4.
Obes Surg ; 28(9): 2617-2625, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-29663250

RESUMO

BACKGROUND: Four commercially available intragastric balloons have been used for the management of obesity and underwent randomized controlled trials (RCTs), and we aimed to compare them using a network meta-analysis approach. METHODS: Several databases were queried from inception to May 26, 2017, and we included RCTs enrolling patients treated with Orbera, Heliosphere, ReShape Duo, and Obalon compared with another balloon, sham, or open-label control group. Two investigators independently abstracted data. A random effects frequentist network meta-analysis and relative ranking of agents using surface under the cumulative ranking probabilities were performed. RESULTS: We included 15 trials at low risk of bias (only two were head-to-head). Compared to control groups, the two fluid-filled devices were associated with significant outcome (% total body weight loss) at 6 months: Orbera, 6.72% (95% CI, 5.55, 7.89) and ReShape Duo 4% (95% CI 2.69, 5.31). Only one of the two gas-filled devices was associated with significant outcome at 6 months: Obalon 3.3% (95% CI 2.30, 4.30), and not the second: Heliosphere 6.71% (95% CI - 0.82, 14.23). Fluid-filled devices had the highest likelihood of superiority in achieving the outcome at 6 months (96.8%) and at 12 months (96.6%). The quality of evidence was high for comparisons against control. CONCLUSIONS: Fluid-filled balloons are more likely to produce weight loss compared to gas-filled balloons or lifestyle intervention. However, they may be associated with a higher rate of intolerance and early removal. This information will aid clinicians in device selection and engaging patients in shared decision-making.


Assuntos
Bariatria , Balão Gástrico , Obesidade/terapia , Bariatria/efeitos adversos , Bariatria/instrumentação , Bariatria/estatística & dados numéricos , Balão Gástrico/efeitos adversos , Balão Gástrico/estatística & dados numéricos , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto , Redução de Peso/fisiologia
5.
Obes Surg ; 28(7): 1860-1868, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29388050

RESUMO

PURPOSE: The objective of this post-market study was to evaluate long-term safety and efficacy of aspiration therapy (AT) in a clinical setting in five European clinics. MATERIALS AND METHODS: The AspireAssist® System (Aspire Bariatrics, Inc. King of Prussia, PA) is an endoscopic weight loss therapy utilizing a customized percutaneous endoscopic gastrostomy tube and an external device to aspirate approximately 30% of ingested calories after a meal, in conjunction with lifestyle counseling. A total of 201 participants, with body mass index (BMI) of 35.0-70.0 kg/m2, were enrolled in this study from June 2012 to December 2016. Mean baseline BMI was 43.6 ± 7.2 kg/m2. RESULTS: Mean percent total weight loss at 1, 2, 3, and 4 years, respectively, was 18.2% ± 9.4% (n/N = 155/173), 19.8% ± 11.3% (n/N = 82/114), 21.3% ± 9.6% (n/N = 24/43), and 19.2% ± 13.1% (n/N = 12/30), where n is the number of measured participants and N is the number of participants in the absence of withdrawals or lost to follow-up. Clinically significant reductions in glycated hemoglobin (HbA1C), triglycerides, and blood pressure were observed. For participants with diabetes, HbA1C decreased by 1% (P < 0.0001) from 7.8% at baseline to 6.8% at 1 year. The only serious complications were buried bumpers, experienced by seven participants and resolved by removal/replacement of the A-Tube, and a single case of peritonitis, resolved with a 2-day course of intravenous antibiotics. CONCLUSION: This study establishes that aspiration therapy is a safe, effective, and durable weight loss therapy in people with classes II and III obesity in a clinical setting. TRIAL REGISTRATION: ISRCTN 49958132.


Assuntos
Bariatria/estatística & dados numéricos , Gastrostomia/estatística & dados numéricos , Obesidade Mórbida/cirurgia , Sistema de Registros , Sucção/instrumentação , Adulto , Idoso , Bariatria/efeitos adversos , Bariatria/instrumentação , Pressão Sanguínea , Índice de Massa Corporal , Diabetes Mellitus , Europa (Continente) , Feminino , Gastrostomia/efeitos adversos , Hemoglobinas Glicadas/metabolismo , Humanos , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Obesidade/complicações , Obesidade Mórbida/sangue , Redução de Peso , Adulto Jovem
6.
Ann Agric Environ Med ; 23(4): 688-691, 2016 12 23.
Artigo em Inglês | MEDLINE | ID: mdl-28030944

RESUMO

Poland is high on a list of countries affected by epidemics of obesity, a problem that has especially suddenly increased in the post-transformation period. MATERIALS AND METHOD: Documentation of 115 subsequent patients diagnosed with grade 3 obesity, considered eligible for surgical treatment, was analysed since 2015. A subgroup of 68 patients was selected from this group and the included patients who decided to cancel their treatment at various stages. Their history since presentation at the obesity treatment centre, BMI with its history, age, education and place of residence were analysed, followed by a telephone survey. 42 patients were finally contacted. Special attention was placed on the analysis of patients taking into account their place of residence. Patients were divided into inhabitants of rural and urban areas. RESULTS: In the study group of 68 patients, 19 (27.9%) were inhabitants of rural areas and 49 (72.1%) of urban areas. Women accounted for 67.6%, and men for 32.4%. The mean age of patients when they presented for treatment was 43 years. On average, men presented 5 years later compared to women. The mean BMI on qualification for treatment of obesity was 47.6 kg/m2. The mean BMI max - 49.6 kg/m2. There were no differences regarding education in both populations. Despite the lack of differences regarding changes in the BMI since withdrawal from treatment, as many as 63% of patients from rural areas reached the BMI max in this time. CONCLUSIONS: There were demographic differences between the degree of obesity observed among patients receiving bariatric treatment, and inhabitants of urban areas were favoured. Patients from rural areas who withdrew from bariatric treatment and were left without medical care significantly more often achieved their maximum body weight, when compared to those living in urban areas. The active participation of physicians, both specialists and general practitioners, in the life of obese patients is imperative.


Assuntos
Bariatria/estatística & dados numéricos , Obesidade/terapia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polônia , População Rural , Fatores Socioeconômicos , População Urbana
8.
J Med Internet Res ; 9(2): e16, 2007 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-17567564

RESUMO

BACKGROUND: Attrition, or dropout, is a problem faced by many online health interventions, potentially threatening the inferential value of online randomized controlled trials. OBJECTIVE: In the context of a randomized controlled trial of an online weight management intervention, where 85% of the baseline participants were lost to follow-up at the 12-month measurement, the objective was to examine the effect of nonresponse on key outcomes and explore ways to reduce attrition in follow-up surveys. METHODS: A sample of 700 non-respondents to the 12-month online follow-up survey was randomly assigned to a mail or telephone nonresponse follow-up survey. We examined response rates in the two groups, costs of follow-up, reasons for nonresponse, and mode effects. We ran several logistic regression models, predicting response or nonresponse to the 12-month online survey as well as predicting response or nonresponse to the follow-up survey. RESULTS: We analyzed 210 follow-up respondents in the mail and 170 in the telephone group. Response rates of 59% and 55% were obtained for the telephone and mail nonresponse follow-up surveys, respectively. A total of 197 respondents (51.8%) gave reasons related to technical issues or email as a means of communication, with older people more likely to give technical reasons for non-completion; 144 (37.9%) gave reasons related to the intervention or the survey itself. Mail follow-up was substantially cheaper: We estimate that the telephone survey cost about US $34 per sampled case, compared to US $15 for the mail survey. The telephone responses were subject to possible social desirability effects, with the telephone respondents reporting significantly greater weight loss than the mail respondents. The respondents to the nonresponse follow-up did not differ significantly from the 12-month online respondents on key outcome variables. CONCLUSIONS: Mail is an effective way to reduce attrition to online surveys, while telephone follow-up might lead to overestimating the weight loss for both the treatment and control groups. Nonresponse bias does not appear to be a significant factor in the conclusions drawn from the randomized controlled trial.


Assuntos
Bariatria/métodos , Obesidade/terapia , Sistemas On-Line , Serviços Postais , Telefone , Bariatria/estatística & dados numéricos , Feminino , Seguimentos , Pesquisas sobre Atenção à Saúde , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Sistemas On-Line/estatística & dados numéricos , Serviços Postais/economia , Serviços Postais/estatística & dados numéricos , Telefone/economia , Telefone/estatística & dados numéricos , Recusa do Paciente ao Tratamento/estatística & dados numéricos , Estados Unidos
10.
JAMA ; 294(15): 1903-8, 2005 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-16234496

RESUMO

CONTEXT: Case series demonstrate that bariatric surgery can be performed with a low rate of perioperative mortality (0.5%), but the rate among high-risk patients and the community at large is unknown. OBJECTIVES: To evaluate the risk of early mortality among Medicare beneficiaries and to determine the relative risk of death among older patients. DESIGN: Retrospective cohort study. SETTING AND PATIENTS: All fee-for-service Medicare beneficiaries, 1997-2002. MAIN OUTCOME MEASURES: Thirty-day, 90-day, and 1-year postsurgical all-cause mortality among patients undergoing bariatric procedures. RESULTS: A total of 16 155 patients underwent bariatric procedures (mean age, 47.7 years [SD, 11.3 years]; 75.8% women). The rates of 30-day, 90-day, and 1-year mortality were 2.0%, 2.8%, and 4.6%, respectively. Men had higher rates of early death than women (3.7% vs 1.5%, 4.8% vs 2.1%, and 7.5% vs 3.7% at 30 days, 90 days, and 1 year, respectively; P<.001). Mortality rates were greater for those aged 65 years or older compared with younger patients (4.8% vs 1.7% at 30 days, 6.9% vs 2.3% at 90 days, and 11.1% vs 3.9% at 1 year; P<.001). After adjustment for sex and comorbidity index, the odds of death within 90 days were 5-fold greater for older Medicare beneficiaries (aged > or =75 years; n = 136) than for those aged 65 to 74 years (n = 1381; odds ratio, 5.0; 95% confidence interval, 3.1-8.0). The odds of death at 90 days were 1.6 times higher (95% confidence interval, 1.3-2.0) for patients of surgeons with less than the median surgical volume of bariatric procedures (among Medicare beneficiaries during the study period) after adjusting for age, sex, and comorbidity index. CONCLUSIONS: Among Medicare beneficiaries, the risk of early death after bariatric surgery is considerably higher than previously suggested and associated with advancing age, male sex, and lower surgeon volume of bariatric procedures. Patients aged 65 years or older had a substantially higher risk of death within the early postoperative period than younger patients.


Assuntos
Bariatria/estatística & dados numéricos , Derivação Gástrica/mortalidade , Gastroplastia/mortalidade , Obesidade Mórbida/cirurgia , Adulto , Idoso , Comorbidade , Feminino , Humanos , Masculino , Medicare , Pessoa de Meia-Idade , Obesidade Mórbida/mortalidade , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Risco , Análise de Sobrevida , Estados Unidos/epidemiologia
11.
JAMA ; 294(15): 1909-17, 2005 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-16234497

RESUMO

CONTEXT: The increasing prevalence and associated sociodemographic disparities of morbid obesity are serious public health concerns. Bariatric surgical procedures provide greater and more durable weight reduction than behavioral and pharmacological interventions for morbid obesity. OBJECTIVE: To examine trends for elective bariatric surgical procedures, patient characteristics, and in-hospital complications from 1998 to 2003 in the United States. DESIGN, SETTING, AND PATIENTS: The Nationwide Inpatient Sample was used to identify bariatric surgery admissions from 1998-2002 (with preliminary data for 12 states from 2003) using International Classification of Diseases, Ninth Revision, codes for foregut surgery with a confirmatory diagnosis of obesity or by diagnosis related group code for obesity surgery. Annual estimates and trends were determined for procedures, patient characteristics, and adjusted complication rates. MAIN OUTCOME MEASURES: Trends in bariatric surgical procedures, patient characteristics, and complications. RESULTS: The estimated number of bariatric surgical procedures increased from 13,365 in 1998 to 72,177 in 2002 (P<.001). Based on preliminary state-level data (1998-2003), the number of bariatric surgical procedures is projected to be 102 794 in 2003. Gastric bypass procedures accounted for more than 80% of all bariatric surgical procedures. From 1998 to 2002, there were upward trends in the proportion of females (81% to 84%; P = .003), privately insured patients (75% to 83%; P = .001), patients from ZIP code areas with highest annual household income (32% to 60%, P<.001), and patients aged 50 to 64 years (15% to 24%; P<.001). Length of stay decreased from 4.5 days in 1998 to 3.3 days in 2002 (P<.001). The adjusted in-hospital mortality rate ranged from 0.1% to 0.2%. The rates of unexpected reoperations for surgical complications ranged from 6% to 9% and pulmonary complications ranged from 4% to 7%. Rates of other in-hospital complications were low. CONCLUSIONS: These findings suggest that use of bariatric surgical procedures increased substantially from 1998 to 2003, while rates of in-hospital complications were stable and length of stay decreased. However, disparities in the use of these procedures, with disproportionate and increasing use among women, those with private insurance, and those in wealthier ZIP code areas should be explored further.


Assuntos
Bariatria/tendências , Gastrectomia/tendências , Derivação Gástrica/tendências , Gastroplastia/tendências , Obesidade Mórbida/cirurgia , Adulto , Idoso , Bariatria/estatística & dados numéricos , Comorbidade , Feminino , Gastrectomia/efeitos adversos , Gastrectomia/estatística & dados numéricos , Derivação Gástrica/efeitos adversos , Derivação Gástrica/estatística & dados numéricos , Gastroplastia/efeitos adversos , Gastroplastia/estatística & dados numéricos , Humanos , Classificação Internacional de Doenças , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Fatores Socioeconômicos , Estados Unidos/epidemiologia
12.
JAMA ; 294(15): 1918-24, 2005 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-16234498

RESUMO

CONTEXT: The use of Roux-en-Y gastric bypass (RYGB) has been reported to be effective in the treatment of obesity and its related comorbidities. Utilization of inpatient services after RYGB is less well understood. OBJECTIVE: To determine the rates and indications for inpatient hospital use before and after RYGB. DESIGN, SETTING, AND PARTICIPANTS: Retrospective study of Californians receiving RYGB in California hospitals from 1995 to 2004. MAIN OUTCOME MEASURE: Hospitalization in the 1 to 3 years after RYGB. RESULTS: In California from 1995 to 2004, 60,077 patients underwent RYGB-11,659 in 2004 alone. The rate of hospitalization in the year following RYGB was more than double the rate in the year preceding RYGB (19.3% vs 7.9%, P<.001). Furthermore, in the subset of patients (n = 24,678) with full 3-year follow-up, a mean of 8.4% were admitted a year before RYGB while 20.2% were readmitted in the year after RYGB, 18.4% in the second year after RYGB, and 14.9% in the third year after RYGB. The most common reasons for admission prior to RYGB were obesity-related problems (eg, osteoarthritis, lower extremity cellulitis), and elective operation (eg, hysterectomy), while the most common reasons for admission after RYGB were complications often thought to be procedure related, such as ventral hernia repair and gastric revision. In multivariate logistic regression models predicting 1-year readmission after RYGB, increasing Charlson Comorbidity Index score, and hospitalization in the 3-year period prior to RYGB were significantly associated with readmission within a year. CONCLUSIONS: Increases in hospital use after surgery appear to be related to RYGB. Payers, clinicians, and patients must consider the not-inconsequential rate of rehospitalization after this type of surgery.


Assuntos
Bariatria/estatística & dados numéricos , Derivação Gástrica/efeitos adversos , Hospitalização/estatística & dados numéricos , Obesidade Mórbida/cirurgia , Adulto , Idoso , California/epidemiologia , Comorbidade , Feminino , Derivação Gástrica/estatística & dados numéricos , Pesquisa sobre Serviços de Saúde , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Obesidade Mórbida/epidemiologia , Readmissão do Paciente , Estudos Retrospectivos
14.
Med J Aust ; 183(6): 310-4, 2005 Sep 19.
Artigo em Inglês | MEDLINE | ID: mdl-16167871

RESUMO

Obesity is shaping up to be the major health care problem and one of the most frequent causes of preventable death in Western countries in the 21st century. Bariatric surgery is the only current treatment that has been shown to achieve major and durable weight loss. Major weight loss in the severely obese leads to total or partial control of a wide range of common and serious diseases, such as diabetes, heart disease and hypertension. Laparoscopic adjustable gastric banding is the most common type of obesity surgery performed in Australia. It is effective, relatively safe and minimally invasive. The blocks to broader application of bariatric surgery should be identified and resolved.


Assuntos
Bariatria/métodos , Obesidade/prevenção & controle , Obesidade/cirurgia , Redução de Peso , Anastomose em-Y de Roux/métodos , Anastomose em-Y de Roux/estatística & dados numéricos , Fármacos Antiobesidade/uso terapêutico , Depressores do Apetite/uso terapêutico , Bariatria/estatística & dados numéricos , Terapia Comportamental/métodos , Desvio Biliopancreático/métodos , Endoscopia Gastrointestinal/métodos , Endoscopia Gastrointestinal/estatística & dados numéricos , Humanos , Obesidade/tratamento farmacológico , Seleção de Pacientes , Qualidade de Vida , Estômago/cirurgia , Resultado do Tratamento
15.
Am Surg ; 71(5): 406-13, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15986971

RESUMO

Identifying risk factors for adverse events after bariatric surgery (BaS) can help define high-risk groups to improve patient safety. We calculated cumulative incidence of adverse events and identified risk factors for these events using validated surgical patient safety indicators (PSIs) developed by the Agency for Healthcare Research and Quality. BaS patients > or =18 years old were identified using the 2002 Nationwide Inpatient Sample. Cumulative incidence at discharge was calculated for accidental puncture or laceration (APL), pulmonary embolus or deep venous thrombosis (PE/DVT), and postoperative respiratory failure (RF). Factors predictive of these PSIs were identified. From 7,853,982 discharges, a national cohort of 69,490 BaS patients was identified. During BaS hospitalization, the cumulative incidences per 1000 discharges of APL, PE/DVT, and RF were 12.6, 3.4, and 7.3, respectively. Risk factors for APL included male gender (odds ratio [OR] 1.6, 95% confidence interval 1.1-2.3, P < 0.05) and age of 40-49 years (OR 1.6 [1.1-2.3], P < 0.05) compared to ages 18-39 years. Patients aged 50-59 years (OR 3.5 [1.6-7.7], P < 0.05) had a higher chance of PE/DVT compared to those 18-39 years. Male gender (OR 1.8 [1.1-2.9], P < 0.05), ages 40-49 (OR 2.1 [1.1-4.2], P < 0.05) and 50-59 (OR 3.8 [2.1-6.9], P < 0.05), a history of chronic lung disease (OR 1.7 [1.1-2.7], P < 0.05), and Medicare coverage compared to private insurance (OR 2.2 [1.2-3.8], P < 0.05) were predictive of RF. This study established national measures for BaS adverse events. Further, risk factors associated with adverse events varied by gender, age, insurance status, and comorbidity. Evaluation of these higher risk BaS groups is needed to improve patient safety.


Assuntos
Bariatria/estatística & dados numéricos , Procedimentos Cirúrgicos do Sistema Digestório/efeitos adversos , Assistência ao Paciente , Complicações Pós-Operatórias/epidemiologia , Segurança , Adolescente , Adulto , Procedimentos Cirúrgicos do Sistema Digestório/estatística & dados numéricos , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Estados Unidos/epidemiologia
16.
Obes Surg ; 15(6): 751-7, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15978141

RESUMO

BACKGROUND: There is a world-wide epidemic of overweight, obesity and morbid obesity. Bariatric surgery today, as the only effective therapy for morbid obesity, is expanding exponentially to meet the global epidemic of morbid obesity. Bariatric surgeons in the Asia-Pacific region had founded the Asia-Pacific Bariatric Surgery Group (APBSG) at Seoul, Korea on October 6, 2004. METHODS: E-mail requests for information were sent to the national bariatric surgery leaders. These requests were followed, if necessary, by second e-mail requests and communications seeking clarification. The summary data was also discussed at the 1st Asia-Pacific Bariatric Consensus Meeting held in Taipei, February 27, 2005. RESULTS: 11 countries or areas in Asia had started bariatric surgery and responded to the general questions. In 2004, 636 bariatric operations were performed by 61 bariatric surgeons. The earliest data for starting bariatric surgery was in 1974 in Taiwan. Following the development of gastric partition, Taiwan performed the first case in 1981, Japan in 1982 and Singapore in 1987. In 2004, 11 countries have started bariatric surgery. The APBSG was founded in 2004. In 2004, 12.1% of operations were open and 87.9% laparoscopic. The 6 most popular operations were: laparoscopic adjustable banding 42.3%; laparoscopic gastric bypass 34.2%; open vertical banded gastroplasty 7.5%; laparoscopic vertical banded gastroplasty 6.3%; laparoscopic sleeve gastrectomy 6.3%; open gastric bypass 4.2%. Pooling open and laparoscopic procedures, relative percentages were gastric banding 42.3%; gastric bypass 38.4%; vertical banded gastroplasty 13.8%. The APBSG consensus meeting recommended bariatric surgery in Asian patients with BMI >37 or >32 with diabetes or two other obesity-related co-morbidities. CONCLUSIONS: Bariatric surgery is expanding rapidly in Asia to meet rapidly increasing obesity. The modification of the indications for bariatric surgery in the Asian is proposed.


Assuntos
Bariatria/estatística & dados numéricos , Procedimentos Cirúrgicos do Sistema Digestório/estatística & dados numéricos , Sudeste Asiático/epidemiologia , Procedimentos Cirúrgicos do Sistema Digestório/tendências , Laparoscopia , Obesidade Mórbida/epidemiologia
17.
J Am Coll Surg ; 201(1): 77-84, 2005 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15978447

RESUMO

BACKGROUND: Exploring bariatric surgery use provides data on effective treatment allocation. This study analyzed national rates of bariatric surgery use and the burden of morbid obesity by gender, census region, and age. STUDY DESIGN: Patients 18 years of age or older undergoing bariatric surgery were identified from the US 2002 Nationwide Inpatient Sample, and the national morbidly obese population 18 years of age or older was determined using the Centers for Disease Control and Prevention 2002 Behavioral Risk Factor Surveillance System databases. General population data were obtained from 2000 census data. Annual rates of bariatric surgery procedures were determined by gender, age group, and census region (Northeast, Midwest, South, and West). Rate ratios were calculated and significance tested through 95% confidence intervals (95% CI), accounting for the Nationwide Inpatient Sample and Behavioral Risk Factor Surveillance System sampling design. RESULTS: In 2002, a national cohort of 69,490 bariatric surgery patients was identified. Of these patients 85% were women and 76% were ages 18 to 49 years. The prevalence of morbid obesity (body mass index > or = 40 kg/m(2)) in the US in 2002 was 1.8%; 60% of morbidly obese people were women, and 63% were ages 18 to 49 years. The rates of bariatric surgery procedures per 100,000 morbidly obese individuals ranged from a low of 139 in men aged 60 years and older in the Midwest to a high of 5,156 in women ages 40 to 49 years in the Northeast. For both men and women, bariatric surgery rates in the West and Northeast were 1.35 (95% CI 1.31 to 1.40, p < 0.05) to 4.51 (95% CI 4.15 to 4.89, p < 0.05) times higher than in the South, respectively; rates in the Midwest were similar to those in the South. CONCLUSIONS: National estimates suggest that bariatric surgery rates do not parallel the burden of morbid obesity by region or age. Additional evaluation of these differences is necessary for optimal bariatric surgery use.


Assuntos
Bariatria/estatística & dados numéricos , Obesidade Mórbida/epidemiologia , Adolescente , Adulto , Fatores Etários , Índice de Massa Corporal , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/cirurgia , Vigilância da População , Prevalência , Fatores Sexuais , Estados Unidos/epidemiologia
18.
Eat Behav ; 6(3): 189-96, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15854865

RESUMO

Bariatric surgery is an increasingly utilized treatment for severe obesity, especially among women. Although African American women have high rates of severe obesity, most research investigating psychological correlates of obesity has been conducted with Caucasians. This study examined the characteristics of African American women seeking bariatric surgery, and ethnic differences in BED rates and correlates of binge eating. Finally, we examined whether the association between psychological factors associated with binge eating was moderated by ethnicity. Results indicated that African American women had higher BMIs, higher self esteem, and less depression than Caucasians. There were no differences in rates of binge eating or BED. Both depression and self esteem accounted for unique variance in binge eating; however, these relationships were not moderated by ethnicity. These results further highlight African Americans' vulnerability to EDs, and suggest that depression and low self esteem are equally relevant to binge eating in African American and Caucasian women.


Assuntos
Bariatria , População Negra/psicologia , Bulimia/etnologia , População Branca/psicologia , Adulto , Bariatria/estatística & dados numéricos , População Negra/estatística & dados numéricos , Índice de Massa Corporal , Bulimia/epidemiologia , Bulimia/psicologia , Comparação Transcultural , Estudos Transversais , Transtorno Depressivo/epidemiologia , Transtorno Depressivo/etnologia , Transtorno Depressivo/psicologia , Feminino , Humanos , Pessoa de Meia-Idade , Inventário de Personalidade/estatística & dados numéricos , Psicometria , Autoimagem , Inquéritos e Questionários , População Branca/estatística & dados numéricos
19.
Obes Surg ; 14(10): 1406-8, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15603660

RESUMO

BACKGROUND: The types of bariatric and the associated operations performed by academic and private surgeons were surveyed. METHODS: A survey containing 8 questions regarding type of practice, type of surgery, associated procedures during bariatric surgery, years in practice and bariatric training was e-mailed to all members of the American Society for Bariatric Surgery. RESULTS: 46% of the members responded and were divided between those who performed their procedures laparoscopically and those who performed open procedures. Laparoscopic adjustable gastric banding was almost exclusively performed in academic centers and encompassed 20% of their bariatric operations, while the gastric bypass was the most common operation performed (65%), followed by vertical banded gastroplasty and duodenal switch. Operations performed simultaneously indicated that cholecystectomies were performed equally in private practice (92.5%) and the academic sector (95%), with higher incidence in open procedures (95%) compared to laparoscopic (40%). Of the surgeons performing appendectomies, 20% were in private practice and 10% in academic. Liver biopsy was performed with the same incidence in private and academic practices (60%). A minority of responders had formal fellowship training (17%), and many had learned from a partner (40%). The approach was dictated by the surgical training (85%) and background. CONCLUSION: No significant difference was found between the private and academic surgeons in performing operations. Appendectomy is rarely performed academically, and cholecystectomy is mostly performed in the open procedure.


Assuntos
Centros Médicos Acadêmicos , Bariatria/organização & administração , Bariatria/estatística & dados numéricos , Procedimentos Cirúrgicos do Sistema Digestório/estatística & dados numéricos , Derivação Gástrica/estatística & dados numéricos , Prática Privada , Prática Profissional/estatística & dados numéricos , Adulto , Atitude do Pessoal de Saúde , Bariatria/normas , Competência Clínica , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Procedimentos Cirúrgicos do Sistema Digestório/normas , Feminino , Derivação Gástrica/métodos , Derivação Gástrica/normas , Gastroplastia/métodos , Gastroplastia/normas , Gastroplastia/estatística & dados numéricos , Pesquisas sobre Atenção à Saúde , Humanos , Laparoscopia/normas , Laparoscopia/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Padrões de Prática Médica/estatística & dados numéricos , Qualidade da Assistência à Saúde , Fatores de Risco , Inquéritos e Questionários , Estados Unidos
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